Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions

Table 1 Summary of existing genome-scale models of M. tuberculosis. iAB-AMØ-1410-Mt-661 has over 2000 genes because it combines an updated version of iNJ661 with a macrophage model

Model	Year	Genes	Reactions	Metabolites	Reference
iNJ661	2007	661	1025	826	[16]
GSMN-TB	2007	726	856	645	[17]
MMF-RmwBo	2009	776	1108	???	[56]
HQMTB	2009	686	607	734	[57]
iNJ661v	2010	663	1049	838	[58]
iAB-AMØ-1410-Mt-661	2010	2071	4489	3400	[14]
MergedTBmodel	2012	917	1400	1017	[59]
GSMN-TB1.1	2013	759	876	667	[60]
iOSDD890	2014	890	1152	961	[20]
sMtb	2014	915	1192	929	[18]
gal2015	2015	760	965	754	[19]
iSM810	2015	810	938	723	[13]
iNJ661mu	2016	672	1057	846	[61]
iEK1011	2017	1011	1228	998	This study

The model provided by Garay et al. was given the name of gal2015 because it is unnamed in the original publication

ISSN: 1752-0509