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Table 1 Summary of existing genome-scale models of M. tuberculosis. iAB-AMØ-1410-Mt-661 has over 2000 genes because it combines an updated version of iNJ661 with a macrophage model

From: Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions

Model Year Genes Reactions Metabolites Reference
iNJ661 2007 661 1025 826 [16]
GSMN-TB 2007 726 856 645 [17]
MMF-RmwBo 2009 776 1108 ??? [56]
HQMTB 2009 686 607 734 [57]
iNJ661v 2010 663 1049 838 [58]
iAB-AMØ-1410-Mt-661 2010 2071 4489 3400 [14]
MergedTBmodel 2012 917 1400 1017 [59]
GSMN-TB1.1 2013 759 876 667 [60]
iOSDD890 2014 890 1152 961 [20]
sMtb 2014 915 1192 929 [18]
gal2015 2015 760 965 754 [19]
iSM810 2015 810 938 723 [13]
iNJ661mu 2016 672 1057 846 [61]
iEK1011 2017 1011 1228 998 This study
  1. The model provided by Garay et al. was given the name of gal2015 because it is unnamed in the original publication