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Fig. 4 | BMC Systems Biology

Fig. 4

From: Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue

Fig. 4

Irradiated and non-irradiated melanoma cells survive in 3D experimental skin models. S100 identifies melanoma cells (brown), and the arrows indicate positive staining. a, c and e Cross-sections through 3D experimental skin models initialised with 1250, 5000 and 8500 non-irradiated melanoma cells, as indicated. b, d, and f Cross-sections through 3D experimental skin models initialised with 1250, 5000 and 8500 irradiated melanoma cells, respectively. Scale bar in each image is 100 μm

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