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Fig. 3 | BMC Systems Biology

Fig. 3

From: Mathematical modelling of interacting mechanisms for hypoxia mediated cell cycle commitment for mesenchymal stromal cells

Fig. 3

Simulation results showing the dynamic change of selected cell cycle regulators under 2% oxygen. This simulation was completed with the nominal model parameter setting. E2F threshold level (E2F_TH) is shown as the horizontal forest green line. The vertical red line indicates commitment time marking the time when E2F level exceeds the threshold level

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