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Fig. 8 | BMC Systems Biology

Fig. 8

From: Feedback regulation in a stem cell model with acute myeloid leukaemia

Fig. 8

Bifurcation diagram in the parameter space of h1 and h2. When h1<0.3689 or h2>0.8861, they could co-compensate the inefficiency of each other in order to maintain in the state of health. However, when h1>0.3689 or h2<0.8861, they induce a state transition, that is, a stable composite state appear. The dynamics of the system can be divided into two classes: (I) healthy steady state and (II) the coexisting steady state of the healthy and leukaemia species (colour online)

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