Fig. 4
From: The innate immune response to ischemic injury: a multiscale modeling perspective
Flow chart of model. The intracellular model is initiated with the intracellular inputs, M2 and DAMPs, at all possible values according to their assigned number of states and simulated until steady states are reached. These steady state values of CCL2 and ROS comprise the inputs to the tissue level model, which simulation results in 3 steady state outcomes representing resolution, overwhelming inflammation or a low percentage of improbable states as described in the text