Fig. 4

Small metabolic network with non-steady state fluxes from time point 1 to 4 (a) to d), respectively). Graphics show the flux carried by each reaction, which changes depending on the time point. The first subindex of the weighting factor \(\alpha _{e_{j,k}}\) indicates the EM E=1. The other two subindices indicate time point j=1,..,4 and reaction k=1,..,8