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Fig. 6 | BMC Systems Biology

Fig. 6

From: Single molecules can operate as primitive biological sensors, switches and oscillators

Fig. 6

Similarities in the topologies of the CO oscillatory network and the KaiC system of cyanobacteria. a CO system (b) KaiABC-system of S. elongatus. KaiA (blue triangle) stimulates the autokinase activity of KaiC to covert the fully dephosphorylated form of KaiC (red) into its fully phosphorylated form (blue). KaiB (flat orange circle) binds to fully phosphorylated KaiC, this leads to the displacement of KaiA and enhances the autophosphatase activity of KaiC. c KaiBC-system of Prochlorococcus. KaiB (flat orange circle) binds KaiC in its fully phosphorylated form (blue) and enhances its autophosphatase activity, but KaiA is missing, so KaiC can phosphorylate itself without support from KaiA [61,62,63,64]

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