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Fig. 3 | BMC Systems Biology

Fig. 3

From: A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice

Fig. 3

The PD modules were consistent with experimental data from diverse sources. a. Temporal simulations for the dynamic changes of trophic form (black curves) and asci (red curves) starting from an initial state with a high level of trophic forms and a low level of asci. b. Temporal simulations (black curves) of the normalized total number of Pneumocystis were compared to the normalized nuclei count from Pneumocystis infected mice (red dots, error bars represent SEM, n = 2 or 3 for each time point). c and d. Histograms showing the distributions of the numbers of the trophic form and asci simulated by the PD module

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