Fig. 4

PcTF-sensitive genes include cell-type specific groups in addition to PUGs. a The Venn diagrams show genes with expression levels that changed at least 2-fold in either direction (q value ≤0.05) at one or more time points in PcTF-expressing cells versus untransfected cells. Red, up-regulated; blue, down-regulated. The heat maps show fold-change (log2(FC)) values for genes that significantly changed (q ≤ 0.05) at all three time points (center regions of the Venn diagrams). The lower left Venn diagram compares these genes between cell types. b Expression profiles (log10(FPKM)) of cells before (UT, untransfected), and 24, 48, or 72 h after PcTF transfection for all genes with expression levels that changed at least 2-fold in either direction (see Venn diagrams in a)