Fig. 1
From: BLASSO: integration of biological knowledge into a regularized linear model
Methodology approach. Classic approach shown on the left side where a linear model with l1-penalty and homogeneous priors is used to predict the vital status of a patient given the RNA-Seq genes expression profile. On the right side, our methodology approach is described using prior biological knowledge obtained from public online resources to consider heterogeneous priors on the estimation of the l1-regularization model