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Table 6 1/2 Cancer related traits from the GWAS Catalog v1.0 (release date: 2017-07-31)

From: Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data

Cancer related traits

Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)

Adverse response to chemotherapy in breast cancer (alopecia)

Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule)

Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU)

Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU)

Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel)

Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel)

Anthracycline-induced cardiotoxicity in childhood cancer

Bladder cancer

Bladder cancer (smoking interaction)

Body mass index (change over time) in cancer

Body mass index (change over time) in cancer or chronic obstructive pulmonary disease

Body mass index (change over time) in gastrointestinal cancer

Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease

Body mass index (change over time) in lung cancer

Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease

Breast cancer

Breast cancer (early onset)

Breast cancer (estrogen-receptor negative

Breast cancer (estrogen-receptor negative)

Breast cancer (estrogen-receptor positive)

Breast cancer (male)

Breast cancer (menopausal hormone therapy interaction)

Breast cancer (prognosis)

Breast cancer (survival)

Breast Cancer in BRCA1 mutation carriers

Breast cancer in BRCA2 mutation carriers

Breast cancer-free interval (treatment with aromatase inhibitor)

Cancer

Cancer (pleiotropy)

Cardia gastric cancer

Cervical cancer

Colon cancer

Colorectal cancer

Colorectal cancer (alcohol consumption interaction)

Colorectal cancer (aspirin and/or NSAID use interaction)

Colorectal cancer (calcium intake interaction)

Colorectal cancer (diet interaction)

Colorectal cancer (interaction)

Colorectal cancer (oestrogen-progestogen hormone therapy interaction)

Colorectal or endometrial cancer

Disease-free survival in breast cancer

Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer

Endometrial cancer

Epithelial ovarian cancer

Erectile dysfunction and prostate cancer treatment

Esophageal cancer

Esophageal cancer (alcohol interaction)

Esophageal cancer (squamous cell)

Esophageal cancer and gastric cancer

Esophageal squamous cell cancer (length of survival)

Estradiol plasma levels (breast cancer)

Estrogen receptor status in breast cancer

Estrogen receptor status in HER2 negative breast cancer

Estrone conjugates/estrone ratio in resected early stage estrogen-receptor positive breast cancer

Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer

Gallbladder cancer

Gastric cancer

Lobular breast cancer (menopausal hormone therapy interaction)

Lung adenocarcinoma

Lung cancer

Lung cancer (asbestos exposure interaction)

Lung cancer (DNA repair capacity)

Lung cancer (smoking interaction)

Multiple cancers (lung cancer

Multiple keratinocyte cancers

Non-cardia gastric cancer