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Table 7 2/2 Cancer related traits from the GWAS Catalog v1.0 (release date: 2017-07-31)

From: Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data

Cancer related traits

Non-melanoma skin cancer

Non-small cell lung cancer

Non-small cell lung cancer (recurrence rate)

Non-small cell lung cancer (survival)

Obesity in adult survivors of childhood cancer exposed to cranial radiation

Obesity in adult survivors of childhood cancer not exposed to cranial radiation

Oral cavity and pharyngeal cancer

Oral cavity cancer

Oropharynx cancer

Ovarian cancer

Ovarian cancer in BRCA1 mutation carriers

Pancreatic cancer

Plasma androstenedione levels in resected early stage-receptor positive breast cancer

Plasma estrone conjugates levels in resected early stage estrogen-receptor positive breast cancer

Plasma estrone levels in resected estrogen-receptor positive breast cancer

Platinum-induced myelosuppression in non-small cell lung cancer

Progression free survival in metastatic colorectal cancer (CAPOX-B vs CAPOX-B plus cetuximab)

Progression free survival in metastatic colorectal cancer (treatment interaction)

Prostate cancer

Prostate cancer (early onset)

Prostate cancer (interaction)

Prostate cancer (survival)

Prostate cancer aggressiveness

Pulmonary function

Response to carboplatin and paclitaxel in ovarian cancer (Caspase 3/7 EC50)

Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50)

Response to carboplatin in ovarian cancer (MTT IC50)

Response to chemotherapy in breast cancer (hypertension) (bevacizumab)

Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab)

Response to gemcitabine in pancreatic cancer

Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer

Response to irinotecan in non-small-cell lung cancer

Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50)

Response to paclitaxel in ovarian cancer (MTT IC50)

Response to Pazopanib in cancer (hepatotoxicity)

Response to platinum-based agents

Response to platinum-based chemotherapy (carboplatin)

Response to platinum-based chemotherapy (cisplatin)

Response to platinum-based chemotherapy in non-small-cell lung cancer

Response to platinum-based neoadjuvant chemotherapy in cervical cancer

Response to radiotherapy in cancer (late toxicity)

Response to radiotherapy in prostate cancer (overall toxicity)

Response to radiotherapy in prostate cancer (toxicity

Response to radiotherapy in prostate cancer (toxicity

Response to radiotherapy in prostate cancer (toxicity

Response to radiotherapy in prostate cancer (toxicity)

Response to tamoxifen in breast cancer

Small-cell lung cancer (survival)

Survival in colon cancer

Survival in colorectal cancer

Survival in colorectal cancer (distant metastatic)

Survival in colorectal cancer (non-distant metastatic)

Survival in endocrine treated breast cancer (estrogen-receptor positive)

Survival in head and neck cancer

Survival in microsatellite instability low/stable colorectal cancer

Survival in rectal cancer

Testicular cancer

Testicular germ cell cancer

Thyroid cancer

Thyroid cancer (Papillary

Urinary bladder cancer

Urinary symptoms in response to radiotherapy in prostate cancer