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Table 3 Model parameter changes corresponding to female adaptations

From: Sex differences in hepatic one-carbon metabolism

PEMT

BHMT

SHMT

MS

MTHFR

SphMy

2.3

0.6

2.2

1.35

0.8

1.3

  1. The Vmax values of the five enzymes in yellow ellipses are multiplied by the factors shown and the concentration of SphMy is multiplied by a factor of 1.3