Fig. 3

Experimental data and weights of the G1/S transition model with 6-parameters. a The solid curve represents the simulated noise-free data obtained from the true parameter. The circles represent simulated experimental data, which is obtained by introducing a small amount of Gaussian noise. This noisy data is used as the observed experimental data in parameter estimation. b Each dot represents the weight of a data point, and the dashed line corresponds to the weights in the equal-weight cost function (“1”). All curves are shown in log scale. The dynamic region receives relatively larger weights and the flat region receives relatively smaller weights