Fig. 11
From: Modeling antibiotic resistance in the microbiota using multi-level Petri Nets
Results for ED2 in case of traditional treatment in which a single high dose of antibiotic is administered to the microbiota. The administration of a single high dose of antibiotics was presented to each microbiota instance. This corresponded to an average onset time for severe resistance (AT) of 162.87 ± 7.78. Simulation tracks from these experiments show healthy individuals (blue curve) progressively acquiring resistance. Some of them reach severe resistance right away (yellow curve), while most of them pass through a phase of mild resistance (orange curve)