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Fig. 12 | BMC Systems Biology

Fig. 12

From: Modeling antibiotic resistance in the microbiota using multi-level Petri Nets

Fig. 12

Results for ED2 in case of innovative treatment in which a single high dose of antibiotic combined with bacterial reintegration is administered to the microbiota. Microbiota reintegration combined with antibiotic administration yields an increased AT (178.64 ± 7.4) with respect to that observed with the administration of the antibiotics alone Fig. 11. In simulation tracks we notice how the overall migration of healthy individuals towards a worsening resistant state slows down, resulting in a slower severe resistance onset time (T)

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