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Table 1 Estimated average mutation rate, initial mutation rate and the value of parameter b based on the clinic data of seven patients from [18] (Survival from diagnosis: month)

From: Instantaneous mutation rate in cancer initiation and progression

Patients Survival from diagnosis Clone time diagnosis Mutations Mutation rate Initial rate b
Pa01C 6 9.8 49 0.0192 0.01917 0.00001
Pa02C 8 9.4 35 0.019 0.0189 0.000018
Pa03C 1 2.4 28 0.0223 0.0201 0.000030
Pa04C 7 7.9 34 0.0188 0.0185 0.000019
Pa05C 10 4.3 28 0.0194 0.0189 0.000029
Pa07C 3 3.1 50 0.0198 0.0198 0.00001
Pa08C 15 10.6 35 0.0193 0.0190 0.000018