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Table 1 Correlation of AURKA expression and clinicopathologic characteristics of PBC in the datasheet of GSE 13507

From: Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer

Characteristic

n

AURKA expression (%)

Pearson χ2

P

High

Low or no

Total

165

30 (18.18)

135 (81.82)

  

Age

   

3.460

0.069

 ≥ 65

96

22 (22.92)

74 (77.08)

  

 < 65

69

8 (11.59)

61 (88.41)

  

Gender

   

1.774

0.196

 Female

30

8 (26.67)

22 (73.33)

  

 Male

135

22 (16.30)

113 (83.70)

  

Tumor stage

   

11.815

0.019*

 Ta

24

3 (12.50)

21 (87.50)

  

 T1

80

8 (10.00)

72 (90.00)

  

 T2a + T2b

31

11 (35.48)

20 (64.52)

  

 T3a + T3b

19

5 (26.31)

14 (73.69)

  

 T4a + T4b

11

3 (27.27)

8 (72.73)

  

Grade

   

17.927

0.000**

 low

105

9 (8.57)

96 (91.43)

  

 high

60

21 (35.00)

39 (65.00)

  

Invasiveness

   

13.229

0.001**

 superical

103

10 (9.71)

93 (90.29)

  

 invasive

62

20 (32.26)

42 (67.74)

  

Systemic chemo

   

0.002

1.000

 Yes

27

5 (18.52)

22 (81.48)

  

 No

138

25 (18.11)

113 (81.89)

  

Lymph node status

   

5.035

0.184

 Nx

1

0 (0.00)

1 (100.00)

  

 N0

149

26 (17.45)

123 (82.55)

  

 N1

8

2 (25.00)

6 (75.00)

  

 N2

6

1 (16.67)

5 (83.33)

  

 N3

1

1 (100.00)

0 (0.00)

  

Progression

   

1.492

0.299

 No

134

22 (16.42)

112 (83.58)

  

 Yes

31

8 (25.81)

23 (74.19)

  

Metastasis

   

0.075

1.000

 No

158

29 (18.35)

129 (81.65)

  

 Yes

7

1 (14.28)

6 (85.72)

  

Cancer-specific survival

   

4.557

0.042*

 Survival

133

20 (15.04)

113 (84.96)

  

 Death

32

10 (31.25)

22 (68.75)

  
  1. *P<0.05, **P<0.01 significant difference between clinicopathologic characteristics of patients with high and low AURKA expression