Table 1 Correlation of AURKA expression and clinicopathologic characteristics of PBC in the datasheet of GSE 13507
From: Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer
| Characteristic | n | AURKA expression (%) | Pearson χ2 | P | |
|---|---|---|---|---|---|
| High | Low or no | ||||
| Total | 165 | 30 (18.18) | 135 (81.82) | ||
| Age | 3.460 | 0.069 | |||
| ≥ 65 | 96 | 22 (22.92) | 74 (77.08) | ||
| < 65 | 69 | 8 (11.59) | 61 (88.41) | ||
| Gender | 1.774 | 0.196 | |||
| Female | 30 | 8 (26.67) | 22 (73.33) | ||
| Male | 135 | 22 (16.30) | 113 (83.70) | ||
| Tumor stage | 11.815 | 0.019* | |||
| Ta | 24 | 3 (12.50) | 21 (87.50) | ||
| T1 | 80 | 8 (10.00) | 72 (90.00) | ||
| T2a + T2b | 31 | 11 (35.48) | 20 (64.52) | ||
| T3a + T3b | 19 | 5 (26.31) | 14 (73.69) | ||
| T4a + T4b | 11 | 3 (27.27) | 8 (72.73) | ||
| Grade | 17.927 | 0.000** | |||
| low | 105 | 9 (8.57) | 96 (91.43) | ||
| high | 60 | 21 (35.00) | 39 (65.00) | ||
| Invasiveness | 13.229 | 0.001** | |||
| superical | 103 | 10 (9.71) | 93 (90.29) | ||
| invasive | 62 | 20 (32.26) | 42 (67.74) | ||
| Systemic chemo | 0.002 | 1.000 | |||
| Yes | 27 | 5 (18.52) | 22 (81.48) | ||
| No | 138 | 25 (18.11) | 113 (81.89) | ||
| Lymph node status | 5.035 | 0.184 | |||
| Nx | 1 | 0 (0.00) | 1 (100.00) | ||
| N0 | 149 | 26 (17.45) | 123 (82.55) | ||
| N1 | 8 | 2 (25.00) | 6 (75.00) | ||
| N2 | 6 | 1 (16.67) | 5 (83.33) | ||
| N3 | 1 | 1 (100.00) | 0 (0.00) | ||
| Progression | 1.492 | 0.299 | |||
| No | 134 | 22 (16.42) | 112 (83.58) | ||
| Yes | 31 | 8 (25.81) | 23 (74.19) | ||
| Metastasis | 0.075 | 1.000 | |||
| No | 158 | 29 (18.35) | 129 (81.65) | ||
| Yes | 7 | 1 (14.28) | 6 (85.72) | ||
| Cancer-specific survival | 4.557 | 0.042* | |||
| Survival | 133 | 20 (15.04) | 113 (84.96) | ||
| Death | 32 | 10 (31.25) | 22 (68.75) | ||