Table 2 Correlation of AURKA expression and clinicopathologic characteristics in the datasheet of GSE31684
From: Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer
| Characteristic | n | AURKA expression (%) | Pearson χ2 | P | |
|---|---|---|---|---|---|
| High | Low or no | ||||
| Total | 93 | 70 (75.27) | 23 (24.73) | ||
| Age | 2.596 | 0.122 | |||
| ≥ 65 | 65 | 52 (80.00) | 13 (20.00) | ||
| < 65 | 28 | 18 (64.29) | 10 (35.71) | ||
| Gender | 0.010 | 1.000 | |||
| Female | 25 | 19 (76.00) | 6 (24.00) | ||
| Male | 68 | 51 (75.00) | 17 (25.00) | ||
| RC stage | 18.766 | 0.001** | |||
| pTa | 5 | 0 (0.00) | 5 (100.00) | ||
| pT1 | 10 | 6 (60.00) | 4 (40.00) | ||
| pT2 | 17 | 13 (76.47) | 4 (23.53) | ||
| pT3 | 42 | 35 (83.33) | 7 (16.67) | ||
| pT4 | 19 | 16 (84.21) | 3 (15.79) | ||
| RC grade | 11.833 | 0.003** | |||
| high | 87 | 69 (78.16) | 18 (21.84) | ||
| low | 6 | 1 (16.67) | 5 (83.33) | ||
| Histology | 2.487 | 0.288 | |||
| TCC | 86 | 63 (73.25) | 23 (26.75) | ||
| TCC/CIS | 2 | 2 (100.00) | 0 (0.00) | ||
| TCC/square | 5 | 5 (100.00) | 0 (0.00) | ||
| Lymph node status | 5.876 | 0.053 | |||
| PN0 | 49 | 32 (65.31) | 17 (34.69) | ||
| PN+ | 28 | 25 (89.28) | 3 (10.72) | ||
| PNx | 16 | 13 (81.25) | 3 (18.75) | ||
| Recurrence | 0.304 | 0.635 | |||
| No | 52 | 38 (73.08) | 14(26.92) | ||
| Yes | 41 | 32 (78.05) | 9 (21.95) | ||
| Last known status | 2.651 | 0.266 | |||
| NED | 28 | 18 (64.28) | 10 (35.72) | ||
| DOC | 27 | 22 (81.48) | 5 (18.52) | ||
| DOD | 38 | 30 (78.95) | 8 (21.05) | ||
| Metastasis | 0.199 | 0.806 | |||
| No | 57 | 42 (73.68) | 15 (26.32) | ||
| Yes | 36 | 28 (77.78) | 8 (22.22) | ||