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Table 4 Significantly affected KEGG pathways derived using GSEA (FDR < 0.25 at 2 or 3 concentrations)

From: Comparative toxicogenomics of three insensitive munitions constituents 2,4-dinitroanisole, nitroguanidine and nitrotriazolone in the soil nematode Caenorhabditis elegans

Pathway ID Size DNAN conc. NTO conc. KEGG pathway name
CEL00350 15 15.5; 62.5   Tyrosine metabolism
CEL00380 14   750; 3000 Tryptophan metabolism
CEL00480 23 1.9; 15.5; 62.5 187; 750; 3000 Glutathione metabolism
CEL00500 14 15.5; 62.5   Starch and sucrose metabolism
CEL00630 14   750; 3000 Glyoxylate and dicarboxylate metabolism
CEL00830 10 15.5; 62.5   Retinol metabolism
CEL00980 25 15.5; 62.5 187; 750; 3000 Metabolism of xenobiotics by cytochrome P450
CEL00982 27 15.5; 62.5 187; 750; 3000 Drug metabolism - cytochrome P450
CEL00983 17 15.5; 62.5   Drug metabolism - other enzymes
CEL01200 25   750; 3000 Carbon metabolism
CEL02010 12 15.5; 62.5   ATP-binding cassette (ABC) transporters
CEL04070 16 1.9; 15.5   Phosphatidylinositol signaling system
CEL04141 60 1.9; 62.5   Protein processing in endoplasmic reticulum
CEL04310 34 1.9; 62.5   Wnt signaling pathway
CEL04350 24 1.9; 62.5   Transforming growth factor beta (TGFβ) signaling pathway