Fig. 1

Gene co-expression analysis using the BrainSpan dataset. a Pie chart of the distribution of genes by biotype for the curated gene set. b Heatmap of module eigengenes from co-expression analysis for all samples chronologically. The row labels correspond to the module (M1 = Module 1) and the column labels indicate the time point ranges (pcw = post conception weeks, mos = months, and yrs. = years). To the right of the heatmap is a color sidebar mapping the enrichment of the modules for lncRNA genes and ASD risk genes respectively. The legend indicates the level of significance with the threshold set at 1.3 or FDR = 0.05 (sig = significance)