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Table 2 Top 15 gene sets in up-superset #1 in BRCA subtype analysis

From: GSAE: an autoencoder with embedded gene-set nodes for genomics functional characterization

Gene Set Terms PScore a gsScore Weightb
CUI_TCF21_TARGETS_2_UP 81.999 0.980 0.198
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 92.578 0.927 −0.154
GRADE_COLON_AND_RECTAL_CANCER_UP 68.314 0.427 0.138
DOANE_BREAST_CANCER_ESR1_DN 87.537 0.374 0.066
VANTVEER_BREAST_CANCER_ESR1_DN 80.186 0.366 0.083
HATADA_METHYLATED_IN_LUNG_CANCER_UP 76.111 0.333 −0.103
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 90.606 0.321 0.079
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP 80.636 0.247 −0.113
BOQUEST_STEM_CELL_DN 10.658 0.245 −0.130
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 54.414 0.228 −0.100
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 88.073 0.206 −0.059
YANG_BREAST_CANCER_ESR1_DN 71.886 0.194 0.088
DOUGLAS_BMI1_TARGETS_DN 18.273 0.177 −0.127
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP 84.141 0.174 −0.076
BERNARD_PPAPDC1B_TARGETS_DN 88.410 0.161 −0.073
  1. aThe PScore of gene set Mann Whitney U test with location shift = 0.5
  2. bThe weight in the model corresponding to the connection of a gene set to the corresponding superset