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Table 6 Top 15 gene sets in the highest ranked superset in LUAD survival analysis

From: GSAE: an autoencoder with embedded gene-set nodes for genomics functional characterization

Gene Set Terms P-valuea gsScore Weightb
CUI_TCF21_TARGETS_2_UP 1.30 × 10− 4 0.446 −0.211
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN 2.02 × 10−4 0.254 −0.201
GROSS_HYPOXIA_VIA_ELK3_UP 5.21 × 10−4 0.245 0.115
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 5.10 × 10−4 0.194 0.145
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 0.0015 0.183 0.107
MITSIADES_RESPONSE_TO_APLIDIN_UP 0.2863 0.159 −0.171
KIM_WT1_TARGETS_DN 0.0064 0.146 0.081
ENK_UV_RESPONSE_EPIDERMIS_UP 1 × 10−5 0.143 0.077
SENESE_HDAC1_TARGETS_DN 0.8285 0.138 −0.162
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 0.1411 0.129 −0.130
YANG_BCL3_TARGETS_UP 0.0299 0.126 0.163
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 0.9507 0.124 0.132
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN 0.0264 0.112 0.147
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 0.0048 0.110 −0.051
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 0.0154 0.107 0.051
  1. aThe P-value of gene set log-rank. bThe weight in the model corresponding to the connection of a gene set to the superset