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Table 4 Gene Ontology terms associated with top 100 hub genes of the early embryonic development-modulated differential network

From: scdNet: a computational tool for single-cell differential network analysis

Category

Term

Gene count

P-value

Annotation Cluster 1 (Enrichment Score: 2.47)

 CC

GO:0043228~non-membrane-bounded organelle

14

4.9 × 10−4

 CC

GO:0043232~intracellular non-membrane-bounded organelle

14

4.9 × 10−4

 CC

GO:0005856~cytoskeleton

6

0.15

Annotation Cluster 2 (Enrichment Score: 1.62)

 MF

GO:0030554~adenyl nucleotide binding

10

1.6 × 10−2

 MF

GO:0001883~purine nucleoside binding

10

1.6 × 10−2

 MF

GO:0001882~nucleoside binding

10

1.7 × 10−2

Annotation Cluster 3 (Enrichment Score: 1.40)

 CC

GO:0005840~ribosome

4

1.3 × 10−2

 BP

GO:0006412~translation

5

1.3 × 10−2

 CC

GO:0030529~ribonucleoprotein complex

5

2.9 × 10−2

Annotation Cluster 4 (Enrichment Score: 0.79)

 BP

GO:0006333~chromatin assembly or disassembly

3

3.9 × 10−2

 CC

GO:0000785~chromatin

3

6.6 × 10−2

 CC

GO:0044427~chromosomal part

3

0.20

Annotation Cluster 5 (Enrichment Score: 0.64)

 CC

GO:0044429~mitochondrial part

4

0.15

 CC

GO:0031967~organelle envelope

4

0.16

 CC

GO:0031975~envelope

4

0.16

  1. Each cluster is represented by the top three terms
  2. Abbreviations: BP biological process, CC cellular component, MF molecular function