Identification of active signaling pathways by integrating gene expression and protein interaction data

BMC Systems Biology

Table 1 SPAGI pathway path background data summary

	For Mouse	For Human
# R, K, TF	2134	2134
# R/K, K/K, K/TF interactions (combined_score > 0)	234,603	249,571
# high-confidence (combined_score > = 700) R/K, K/K, K/TF interactions (assuming bi-directional interaction)	33,100	39,004
# common interaction	27,790
# combined unique interaction	44,314
# high-confidence complete R/K/TF paths	102,842
# high-confidence complete R/K/TF paths without housekeeping gene paths (# of R-defined pathways)	89,161 (548)

ISSN: 1752-0509