TY - JOUR AU - Liu, Quanya AU - Chen, Peng AU - Wang, Bing AU - Zhang, Jun AU - Li, Jinyan PY - 2018 DA - 2018/12/31 TI - Hot spot prediction in protein-protein interactions by an ensemble system JO - BMC Systems Biology SP - 132 VL - 12 IS - 9 AB - Hot spot residues are functional sites in protein interaction interfaces. The identification of hot spot residues is time-consuming and laborious using experimental methods. In order to address the issue, many computational methods have been developed to predict hot spot residues. Moreover, most prediction methods are based on structural features, sequence characteristics, and/or other protein features. SN - 1752-0509 UR - https://doi.org/10.1186/s12918-018-0665-8 DO - 10.1186/s12918-018-0665-8 ID - Liu2018 ER -