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Table 4 Prediction comparison of different methods on BID test sets

From: Hot spot prediction in protein-protein interactions by an ensemble system

Method Features ACC F1 PRE
Hot point Structural features 0.72 0.49 0.55
ppRF B-factor, individual atomic contacts and the co-occurring contacts 0.78 0.58 0.69
HEP Physicochemical, structural neighborhood features 0.79 0.70 0.60
PredHS Structural neighborhood features 0.88 0.76 0.79
Hu method Sequence features 0.76 0.80 1.0
Our method Sequence features 0.92 0.89 0.95