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Fig. 1 | BMC Systems Biology

Fig. 1

From: An agent-based model of the Notch signaling pathway elucidates three levels of complexity in the determination of developmental patterning

Fig. 1

The cellular events of N signaling pathway. The steps are (1) N and Dl proteins are transcribed, translated and transported to the cell membrane; (2) Dl undergoes an endocytic processing step to become the ligand for N; (3) the Dl ligand and N receptor interact resulting in a cleavage and endocytosis of a N fragment; (4) A second cleavage releases a N product that is translocated to the nucleus

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