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Table 1 Structural properties of pathway crosstalk perturbation networks for the transitions. Specific density refers to the number of perturbed crosstalk regions compared against the total number of possible crosstalks between the pathways in the network. HTD, health to disease; DTT, disease to treatment; TTH, treatment to health

From: Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone

 

HTD

DTT

TTH

Nodes

104

78

110

Edges

222

149

213

Density

0.041

0.050

0.036

Specific density

222/1116

149/566

213/1051

Average degree

4.27

3.82

3.87

Clustering coefficient

0.579

0.620

0.513

Average shortest path

3.71

1.99

3.72

Connected components

22

16

19

Single nodes

14

7

11