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Table 3 Initial conditions

From: Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus

Node Initial value Reason
Apoptosis False We set apoptosis to False to see whether the input signals can cause apoptosis
Caspases 3, 6, 7, 8, 9 False Caspases serve as the final mediators of apoptosis. So, we set them to False to see whether the input signals can activate them