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Table 1 Performance of predicting GRN with different PPINs on 30 yeast genes ground-truth network

From: Fusing gene expressions and transitive protein-protein interactions for inference of gene regulatory networks

Method

TP

FP

FN

Prec.(%)

Rec.(%)

F1(%)

AUROC

AUPR

Raw PPIN

165

95

152

63.46

52.05

57.19

0.698

0.591

Extended PPIN (subnet)

229

220

88

51.00

72.24

59.79

0.713

0.533

Extended PPIN (global)

240

260

77

48.00

75.71

58.75

0.696

0.500

  1. Best performance measures that are significantly different are shown in bold