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Table 3 Performance of GRNs generated from the BGM with different priors on 30 yeast genes ground-truth network

From: Fusing gene expressions and transitive protein-protein interactions for inference of gene regulatory networks

Method

TP

FP

FN

Prec.(%)

Rec.(%)

F1(%)

AUROC

AUPR

Time(sec)

BGM

139

201

178

40.88

43.85

42.31

0.553

0.390

636

BGM (GMM)

185

293

132

38.70

58.36

46.54

0.555

0.383

606

BGM (C scores)

170

150

147

53.13

53.63

53.38

0.653

0.490

518

Nariai et al. (GHMM)

176

273

141

39.20

55.52

45.95

0.570

0.408

1174

Imoto et al. (GHMM)

184

293

133

38.57

58.04

46.35

0.565

0.401

1150

BGM (R scores)

202

237

115

46.01

63.72

53.44

0.627

0.446

608

  1. Best performance measures that are significantly different are shown in bold
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BMC Systems Biology

ISSN: 1752-0509

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