Table 3 Top-50 candidate miRNAs for lung cancer predicted by PMAMCA. Validation was performed utilizing HMDD, miR2Disease, dbDEMC, and literature analysis. All 50 miRNAs were confirmed to be related to lung cancer
From: PMAMCA: prediction of microRNA-disease association utilizing a matrix completion approach
Rank | Name | Evidence | Rank | Name | Evidence |
|---|---|---|---|---|---|
1 | hsa-let-7a | miR2Disease, dbDEMC | 26 | hsa-let-7e | miR2Disease, dbDEMC |
2 | hsa-mir-145 | miR2Disease, dbDEMC | 27 | hsa-mir-1 | miR2Disease, dbDEMC |
3 | hsa-mir-17 | dbDEMC | 28 | hsa-mir-101 | miR2Disease, dbDEMC |
4 | hsa-let-7b | miR2Disease, dbDEMC | 29 | hsa-let-7i | dbDEMC |
5 | hsa-mir-15a | dbDEMC | 30 | hsa-mir-182 | miR2Disease, dbDEMC |
6 | hsa-mir-155 | miR2Disease, dbDEMC | 31 | hsa-mir-181a | dbDEMC |
7 | hsa-mir-16 | miR2Disease, dbDEMC | 32 | hsa-mir-191 | miR2Disease, dbDEMC |
8 | hsa-mir-125b | dbDEMC | 33 | hsa-mir-141 | miR2Disease, dbDEMC |
9 | hsa-mir-126 | miR2Disease, dbDEMC | 34 | hsa-mir-150 | miR2Disease, dbDEMC |
10 | hsa-mir-148a | dbDEMC | 35 | hsa-mir-139 | miR2Disease, dbDEMC |
11 | hsa-mir-183 | miR2Disease, dbDEMC | 36 | hsa-mir-138 | dbDEMC |
12 | hsa-let-7g | miR2Disease, dbDEMC | 37 | hsa-mir-107 | dbDEMC |
13 | hsa-let-7c | miR2Disease, dbDEMC | 38 | hsa-mir-127 | Literature [42] |
14 | hsa-mir-146a | miR2Disease, dbDEMC | 39 | hsa-mir-140 | miR2Disease, dbDEMC |
15 | hsa-mir-100 | dbDEMC | 40 | hsa-mir-133b | miR2Disease, dbDEMC |
16 | hsa-mir-146b | miR2Disease, dbDEMC | 41 | hsa-mir-18b | dbDEMC |
17 | hsa-mir-125a | miR2Disease, dbDEMC | 42 | hsa-mir-130b | dbDEMC |
18 | hsa-mir-15b | dbDEMC | 43 | hsa-mir-130a | miR2Disease, dbDEMC |
19 | hsa-let-7d | miR2Disease, dbDEMC | 44 | hsa-mir-132 | dbDEMC |
20 | hsa-let-7f | miR2Disease, dbDEMC | 45 | hsa-mir-133a | dbDEMC |
21 | hsa-mir-10b | dbDEMC | 46 | hsa-mir-185 | dbDEMC |
22 | hsa-mir-143 | miR2Disease, dbDEMC | 47 | hsa-mir-106b | dbDEMC |
23 | hsa-mir-142 | Unconfirmed [41] | 48 | hsa-mir-135b | dbDEMC |
24 | hsa-mir-18a | miR2Disease, dbDEMC | 49 | hsa-mir-149 | dbDEMC |
25 | hsa-mir-181b | dbDEMC | 50 | hsa-mir-106a | miR2Disease, dbDEMC |