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Fig. 1 | BMC Systems Biology

Fig. 1

From: How to schedule VEGF and PD-1 inhibitors in combination cancer therapy?

Fig. 1

Interaction of immune cells with cancer cells. Sharp arrows indicate proliferation/activation, blocked arrows indicate killing/blocking, and the inverted arrow indicates recruitment/chemoattraction. C: cancer cells, D: dentritic cells, T1: CD 4+ Th1 cells, T8: CD 8+ T cells, Treg: T regulatory cells, Endo: endothelial cells, Ox: Oxygen from the blood. T1 and T8 cells and Tregs express PD-1 and PD-L1; tumor expresses PD-L1

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