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Networks and information flow

Page 4 of 4

  1. Metabolic interactions involve the exchange of metabolic products among microbial species. Most microbes live in communities and usually rely on metabolic interactions to increase their supply for nutrients an...

    Authors: Eleftheria Tzamali, Panayiota Poirazi, Ioannis G Tollis and Martin Reczko

    Citation: BMC Systems Biology 2011 5:167

    Content type: Research article

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  2. Yersinia pestis is a gram-negative bacterium that causes plague, a disease linked historically to the Black Death in Europe during the Middle Ages and to several outbreaks during the modern era. Metabolism in Y. ...

    Authors: Pep Charusanti, Sadhana Chauhan, Kathleen McAteer, Joshua A Lerman, Daniel R Hyduke, Vladimir L Motin, Charles Ansong, Joshua N Adkins and Bernhard O Palsson

    Citation: BMC Systems Biology 2011 5:163

    Content type: Research article

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  3. It has been shown in experimental and theoretical work that covalently modified signaling cascades naturally exhibit bidirectional signal propagation via a phenomenon known as retroactivity. An important conse...

    Authors: Michelle L Wynn, Alejandra C Ventura, Jacques A Sepulchre, Héctor J García and Sofia D Merajver

    Citation: BMC Systems Biology 2011 5:156

    Content type: Research article

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  4. Neuronal migration, the process by which neurons migrate from their place of origin to their final position in the brain, is a central process for normal brain development and function. Advances in experimenta...

    Authors: Yaki Setty, Chih-Chun Chen, Maria Secrier, Nikita Skoblov, Dimitrios Kalamatianos and Stephen Emmott

    Citation: BMC Systems Biology 2011 5:154

    Content type: Research article

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  5. The chemotaxis pathway in the bacterium Escherichia coli allows cells to detect changes in external ligand concentration (e.g. nutrients). The pathway regulates the flagellated rotary motors and hence the cells' ...

    Authors: Diana Clausznitzer and Robert G Endres

    Citation: BMC Systems Biology 2011 5:151

    Content type: Research article

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  6. Purple nonsulfur bacteria (PNSB) are facultative photosynthetic bacteria and exhibit an extremely versatile metabolism. A central focus of research on PNSB dealt with the elucidation of mechanisms by which the...

    Authors: Oliver Hädicke, Hartmut Grammel and Steffen Klamt

    Citation: BMC Systems Biology 2011 5:150

    Content type: Research article

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  7. A biological system's robustness to mutations and its evolution are influenced by the structure of its viable space, the region of its space of biochemical parameters where it can exert its function. In system...

    Authors: Elías Zamora-Sillero, Marc Hafner, Ariane Ibig, Joerg Stelling and Andreas Wagner

    Citation: BMC Systems Biology 2011 5:142

    Content type: Methodology article

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  8. As a group of highly conserved small non-coding RNAs with a length of 21~23 nucleotides, microRNAs (miRNAs) regulate the gene expression post-transcriptionally by base pairing with the partial or full compleme...

    Authors: Wei Zhou, Yan Li, Xia Wang, Lianqi Wu and Yonghua Wang

    Citation: BMC Systems Biology 2011 5:141

    Content type: Research article

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  9. Orthologous genes are highly conserved between closely related species and biological systems often utilize the same genes across different organisms. However, while sequence similarity often implies functiona...

    Authors: Guy E Zinman, Shan Zhong and Ziv Bar-Joseph

    Citation: BMC Systems Biology 2011 5:134

    Content type: Research article

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  10. Gene and protein interactions are commonly represented as networks, with the genes or proteins comprising the nodes and the relationship between them as edges. Motifs, or small local configurations of edges an...

    Authors: Fergal Casey, Nevan Krogan, Denis C Shields and Gerard Cagney

    Citation: BMC Systems Biology 2011 5:133

    Content type: Research article

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  11. Extensive variation in early gap gene expression in the Drosophila blastoderm is reduced over time because of gap gene cross regulation. This phenomenon is a manifestation of canalization, the ability of an organ...

    Authors: Vitaly V Gursky, Lena Panok, Ekaterina M Myasnikova, M Manu, Maria G Samsonova, John Reinitz and Alexander M Samsonov

    Citation: BMC Systems Biology 2011 5:118

    Content type: Research article

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  12. Chaperonins are important in living systems because they play a role in the folding of proteins. Earlier comprehensive analyses identified substrate proteins for which folding requires the chaperonin GroEL/Gro...

    Authors: Kazuhiro Takemoto, Tatsuya Niwa and Hideki Taguchi

    Citation: BMC Systems Biology 2011 5:98

    Content type: Research article

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  13. miRNAs are a class of non-coding RNA molecules that play crucial roles in the regulation of virus-host interactions. The ever-increasing data of known viral miRNAs and human protein interaction network (PIN) h...

    Authors: Zhenpeng Li, Fei Li, Ming Ni, Peng Li, Xiaochen Bo and Shengqi Wang

    Citation: BMC Systems Biology 2011 5:93

    Content type: Research article

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  14. Network modeling of whole transcriptome expression data enables characterization of complex epistatic (gene-gene) interactions that underlie cellular functions. Though numerous methods have been proposed and s...

    Authors: Jen-hwa Chu, Ross Lazarus, Vincent J Carey and Benjamin A Raby

    Citation: BMC Systems Biology 2011 5:89

    Content type: Methodology article

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  15. BMP6 mediated osteoblast differentiation plays a key role in skeletal development and bone disease. Unfortunately, the signaling pathways regulated by BMP6 are largely uncharacterized due to both a lack of dat...

    Authors: Weijun Luo, Michael S Friedman, Kurt D Hankenson and Peter J Woolf

    Citation: BMC Systems Biology 2011 5:82

    Content type: Research article

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  16. The molecular circuitry of living organisms performs remarkably robust regulatory tasks, despite the often intrinsic variability of its components. A large body of research has in fact highlighted that robustn...

    Authors: Franco Blanchini and Elisa Franco

    Citation: BMC Systems Biology 2011 5:74

    Content type: Methodology article

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  17. Domains are basic units of proteins, and thus exploring associations between protein domains and human inherited diseases will greatly improve our understanding of the pathogenesis of human complex diseases an...

    Authors: Wangshu Zhang, Yong Chen, Fengzhu Sun and Rui Jiang

    Citation: BMC Systems Biology 2011 5:55

    Content type: Research article

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  18. Genetically identical cells often show significant variation in gene expression profile and behaviour even in the same physiological condition. Notably, embryonic cells destined to the same tissue maintain a u...

    Authors: Yasushi Saka, Cédric Lhoussaine, Celine Kuttler, Ekkehard Ullner and Marco Thiel

    Citation: BMC Systems Biology 2011 5:54

    Content type: Research article

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  19. The 3D structure of the chromosome of the model organism Escherichia coli is one key component of its gene regulatory machinery. This type of regulation mediated by topological transitions of the chromosomal DNA ...

    Authors: Nikolaus Sonnenschein, Marcel Geertz, Georgi Muskhelishvili and Marc-Thorsten Hütt

    Citation: BMC Systems Biology 2011 5:40

    Content type: Research article

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  20. RNA interference (RNAi) is a regulatory cellular process that controls post-transcriptional gene silencing. During RNAi double-stranded RNA (dsRNA) induces sequence-specific degradation of homologous mRNA via ...

    Authors: Giulia Cuccato, Athanasios Polynikis, Velia Siciliano, Mafalda Graziano, Mario di Bernardo and Diego di Bernardo

    Citation: BMC Systems Biology 2011 5:19

    Content type: Research article

    Published on:

2017 Journal Metrics

  • Citation Impact
    2.05 - 2-year Impact Factor
    2.505 - 5-year Impact Factor
    0.689 - Source Normalized Impact per Paper (SNIP)
    1.109 - SCImago Journal Rank (SJR)

    Usage 
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    Social Media Impact
    523 mentions

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