A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanisms
Ataxia telangiectasia mutated (ATM) is a detector of double-strand breaks (DSBs) and a crucial component of the DNA damage response (DDR) along with p53 and NF- κB transcription factors and Wip1 phosphatase. Desp...