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Table 6 Effect of ceramide inhibition on the toxicity of palmitate

From: A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells

Treatment

C16 Ceramide (pmol/mg protein)

LDH released (%)

Control (BSA)

0.63 ± 0.28 *

1.27 ± 0.48 *

Palmitate

24.44 ± 6.39

4.71 ± 1.67

Fumonisin B1

6.80 ± 2.85 *

5.15 ± 1.38

  1. *, significantly lower than palmitate
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BMC Systems Biology

ISSN: 1752-0509

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