Table 2 Growth phenotypes of the core model. Consistent organizations in the core network model of the regulated central metabolism of E. coli, ordered by size.

1

Input metabolites, ADP, PI, ArcA, Fnr, GalR, GalS, GlpR, LacI, Mlc, PykF, Ubiquitous proteins

-

2

Input metabolites, ADP, O2, O2xt, PI, GalR, GalS, GlpR, LacI, Mlc, PykF, Ubiquitous proteins

O2

3

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GalR, GalS, GlpR, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC

4

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GlpR, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, LCTS

5

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GalR, GalS, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, GL

6

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, GL, LCTS

7

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, NADH, PI, PPI, UDPG, Crr, FadR, Food, GalP, GalR, GalS, GlpR, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, O2

8

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, FadR, Food, GalP, GlpR, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, LCTS, O2

9

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, NADH, PI, PPI, UDPG, Crr, FadR, Food, GalP, GalR, GalS, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, GL, O2

10

Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, FadR, Food, GalP, Pgk, PtsGHI, PykF, Ubiquitous proteins

GLC, GL, LCTS, O2

11

Input metabolites, Glycolysis metabolites, ADP, G1P, GL, GL3P, GLxt, NADH, NADPH, O2, O2xt, PI, PPI, QH2, UDPG, ArcA, Crr, Fnr, Food, GalP, GalR, GalS, GlpABC, GlpF, GlpK, LacI, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins

GL

12

Input metabolites, Glycolysis metabolites, ADP, G1P, GL, GL3P, GLxt, NADH, NADPH, PI, PPI, QH2, UDPG, Crr, Food, GalP, GalR, GalS, GlpD, GlpF, GlpK, LacI, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins

GL, O2

13

Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, LCTS, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, Fnr, Food, GalE, GalK, GalM, GalP, GalT, GlpR, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins

LCTS

14

Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, LCTS, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, Fnr, Food, GalE, GalK, GalM, GalP, GalT, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins

GL, LCTS

15

Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, GLxt, LCTS, LCTSxt, NADH, PI, PPI, UDPG, Crr, Food, GalE, GalK, GalM, GalP, GalT, GlpR, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins

LCTS, O2

16

Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, GLxt, LCTS, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, Food, GalE, GalK, GalM, GalP, GalT, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins

GL, LCTS, O2