| Candidate Genes from Standard Gene Name and Genbank Accession | Pearson correlations with gene expression profiles | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  | MEblue | CFS Severity | TPH2 SNP | |||||||
 |  | r: All | Rank1 | r: All | p-value | r: M | r: F | r: All | p-value | r: M | r: F |
1 | DGCR8 (AF165527) | 0.81 | 329 | 0.37 | <0.001 | 0.35 | 0.39 | 0.13 | 0.14 | 0.12 | 0.12 |
2 | PPARD (BC002715) | 0.54 | 2305 | 0.37 | 0.001 | 0.49 | 0.34 | 0.10 | 0.25 | 0.18 | 0.08 |
3 | IHPK2 (BC004469) | 0.48 | 2842 | 0.36 | 0.001 | 0.36 | 0.36 | 0.15 | 0.09 | 0.02 | 0.16 |
4 | CCDC92 (AB015292) | 0.43 | 3434 | 0.35 | 0.001 | 0.33 | 0.38 | 0.07 | 0.42 | -0.07 | 0.10 |
5 | NR5A2 (AB019246) | 0.47 | 2945 | 0.35 | 0.001 | 0.37 | 0.32 | 0.10 | 0.27 | 0.18 | 0.07 |
6 | PDPK1 (BC006339) | 0.67 | 1218 | 0.35 | 0.001 | 0.47 | 0.31 | 0.16 | 0.08 | 0.24 | 0.12 |
7 | NXF1 (AF112880) | 0.63 | 1517 | 0.34 | 0.001 | 0.17 | 0.36 | 0.15 | 0.10 | -0.03 | 0.15 |
8 | COL13A1 (NM_080804) | 0.51 | 2590 | 0.34 | 0.001 | 0.25 | 0.34 | 0.05 | 0.60 | -0.10 | 0.06 |
9 | AXIN2 (AF078165) | 0.80 | 414 | 0.33 | 0.002 | 0.39 | 0.32 | 0.13 | 0.15 | 0.16 | 0.10 |
10 | SCAP (AK075528) | 0.64 | 1458 | 0.33 | 0.002 | 0.44 | 0.36 | 0.17 | 0.06 | 0.38 | 0.12 |
11 | DFFA (AF087573) | 0.71 | 948 | 0.33 | 0.002 | 0.25 | 0.35 | 0.11 | 0.21 | 0.07 | 0.10 |
12 | TCF4 (M74719) | 0.76 | 637 | 0.33 | 0.002 | 0.38 | 0.31 | 0.14 | 0.13 | 0.15 | 0.11 |
13 | WNT16 (NM_016087) | 0.71 | 910 | 0.33 | 0.002 | 0.38 | 0.32 | 0.08 | 0.36 | 0.13 | 0.05 |
14 | ZNF687 (BC032463) | 0.83 | 243 | 0.33 | 0.002 | 0.53 | 0.30 | 0.10 | 0.28 | 0.29 | 0.04 |
15 | FGF1 (BC032697) | 0.65 | 1378 | 0.32 | 0.003 | 0.26 | 0.31 | 0.02 | 0.83 | -0.03 | 0.00 |
16 | ANKRD6 (BC001078) | 0.83 | 241 | 0.31 | 0.003 | 0.36 | 0.28 | 0.14 | 0.12 | 0.23 | 0.09 |
17 | EPHX1 (M36374) | 0.64 | 1442 | 0.31 | 0.003 | 0.24 | 0.33 | 0.11 | 0.22 | -0.01 | 0.12 |
18 | FAIM (AK001444) | 0.86 | 132 | 0.31 | 0.004 | 0.34 | 0.30 | 0.07 | 0.43 | 0.11 | 0.04 |
19 | ZMYND11 (NM_006624) | 0.67 | 1223 | 0.31 | 0.004 | 0.47 | 0.26 | 0.13 | 0.15 | 0.32 | 0.07 |
20 | ADFP (NM_001122) | 0.69 | 1057 | 0.31 | 0.004 | 0.27 | 0.32 | 0.11 | 0.20 | 0.12 | 0.10 |
21 | BAT5 (BC031839) | 0.73 | 802 | 0.31 | 0.004 | 0.27 | 0.31 | 0.10 | 0.24 | 0.08 | 0.09 |
22 | CEBPA (NM_004364) | 0.70 | 980 | 0.31 | 0.004 | 0.16 | 0.32 | 0.08 | 0.38 | -0.16 | 0.10 |
23 | HNRNPA1 (NM_002136) | 0.46 | 3048 | 0.30 | 0.004 | 0.23 | 0.34 | 0.11 | 0.23 | -0.12 | 0.15 |
24 | DMBT1 (NM_004406) | 0.59 | 1874 | 0.30 | 0.005 | 0.50 | 0.24 | 0.08 | 0.37 | 0.20 | 0.03 |
25 | RNASEN (AF116910) | 0.75 | 680 | 0.30 | 0.005 | 0.29 | 0.31 | 0.10 | 0.26 | 0.09 | 0.08 |
26 | EDAR (AF130988) | 0.82 | 288 | 0.30 | 0.005 | 0.20 | 0.33 | 0.09 | 0.32 | -0.02 | 0.09 |
27 | F3 (AF540377) | 0.67 | 1181 | 0.30 | 0.005 | 0.28 | 0.30 | 0.10 | 0.26 | 0.18 | 0.06 |
28 | HSPG2 (AL445795) | 0.30 | 4880 | 0.30 | 0.005 | 0.09 | 0.33 | -0.03 | 0.71 | -0.25 | -0.02 |
29 | EIF2C2 (AF121255) | 0.60 | 1760 | 0.30 | 0.005 | 0.29 | 0.27 | 0.18 | 0.04 | 0.27 | 0.13 |
 | Median2: | 0.67 | 1218 | 0.32 | 0.003 | 0.33 | 0.32 | 0.10 | 0.24 | 0.13 | 0.09 |