Figure 1From: BowTieBuilder: modeling signal transduction pathwaysAssumed structure of signaling pathways. This figure depicts a signal transduction pathway. The source proteins are cell-surface proteins that transduce the signal to intermediate (cytosolic) proteins. These in turn transduce the signal to the target proteins (TFs), that regulate the transcription of downstream genes. A dotted line between two proteins indicates a PPI.Back to article page