From: Dynamical modeling of microRNA action on the protein translation process
Observable value | Initiation(k1) | Step after initiation(k2) | Ribosome assembly (k3) | Elongation (k4) |
---|---|---|---|---|
Wild-type cap, inefficient initiation | ||||
Steady-state rate | slightly decreases | decreases | no change | decreases after threshold |
Relaxation time | no change | no change | no change | goes up and down |
Wild-type cap, efficient initiation | ||||
Steady-state rate | no change | slightly decreases after strong inhibition | no change | decreases |
Relaxation time | no change | goes up and down | no change | no change |
A-cap, inefficient initiation | ||||
Steady-state rate | decreases | decreases | no change | slightly decreases after strong inhibition |
Relaxation time | no change | no change | no change | goes up and down |
A-cap, efficient initiation | ||||
Steady-state rate | decreases after threshold | slightly decreases after strong inhibition | no change | decreases |
Relaxation time | goes up and down | goes up and down | no change | increases |