Experimental and computational validation of models of fluorescent and luminescent reporter genes in bacteria

BMC Systems Biology

Table 1 Variables and constants used in the models of the expression of the host and reporter genes.

	Concentration variables
m(t)	host mRNA concentration [M]	n(t)	reporter mRNA concentration [M]
p(t)	host protein concentration [M]	q(t)	total reporter protein concentration [M]
		r(t)	active reporter protein concentration [M]
	Promoter activity and growth rate
f(t)	promoter activity [dimensionless]	μ(t)	growth rate [min^-1]
	Kinetic constants
κ _m	transcription rate constant [M min¹]	κ _p	translation rate constant [min^-1]
		κ _r	folding rate constant [min^-1]
γ _m	host mRNA degradation constant [min^-1]	γ _n	reporter mRNA degradation constant [min^-1]
γ _p	host protein degradation constant [min^-1]	γ _q	reporter protein degradation constant [min^-1]

ISSN: 1752-0509