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Figure 9 | BMC Systems Biology

Figure 9

From: A Systems Biology Strategy for Predicting Similarities and Differences of Drug Effects: Evidence for Drug-specific Modulation of Inflammation in Atherosclerosis

Figure 9

Validation of in vivo endpoint effects of the drugs on early atherosclerosis. Atherosclerotic lesion area determined in the aortic valve area of ApoE3Leiden mice treated with an atherogenic high cholesterol diet (HC) in the presence or absence of rosuvastatin (RSV), fenofibrate (FF) and LXR agonist T0901317 (T09). *P<0.05 versus HC (ANOVA and least significant difference post-hoc testing).

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BMC Systems Biology

ISSN: 1752-0509

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