Figure 7

The impact of absolute 5'-initiation rate and scanning rate on 5'-polysome size (Model 3). 5'-initiation rate ' is changed proportionally with scanning rate (from 5 nt/s to 100 nt/s), and maintains a constant ratio such that the relative 5'-initiation rate is 1. Fold = a _S /30. The other rates, including those of 60S subunit joining (30 nt/s), translation elongation and termination (calculated by Gilchrist and Wagner, [15]) were kept constant. Ternary complex binding rates a _TC under the two conditions predicted by Model 2 were used to generate the simulations. Each data point represents an average of 50 replicates, in the same way as in Figure 6.