Prioritizing cancer-related genes with aberrant methylation based on a weighted protein-protein interaction network

Table 1 Genes validated using PubMed literature co-citations

Symbol	Entrez gene ID	Diagnostic marker	prognostic marker	DrugBank
CREBBP*	1387	▲		target
EP300*	2033	▲	⋆
HIF1A*	3091		⋆	target
PRMT1*	3276	▲	⋆	target
PML*	5371		⋆
med1*	5469			target
tp63*	8626	▲	⋆
PRKCDBP*	112464	▲
MANEAL*	149175
Rasef*	158158

The star (*) in the top right corner of the first column represents this gene is methylated aberrantly in cancers validated by literature. The triangle (▲) in the second column represents this gene can be a diagnostic marker for diseases. And the pentagram (⋆) in the third column represents this gene can be a prognostic marker for diseases supported by literature.

ISSN: 1752-0509