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Figure 5 | BMC Systems Biology

Figure 5

From: Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

Figure 5

qPCR analysis of mRNAs in PKD at embryonic age 14. Expression of 12 genes (Ddx3y, Adam22, Cpeb3, Sox6, Edil3, Mysm1, Pitx2, F2rl2, Grap2, P2rx7, Fgfr3 and Fgf10) significantly regulated on mRNA microarray was verified using qPCR assays. Ddx3y, Adam22, Cpeb3, Sox6 and Edil3 were down-regulated in Pkd1-/-kidneys. Mysm1, Pitx2, F2rl2, Grap2, P2rx7, Fgfr3 and Fgf10 were up-regulated in Pkd1-/-kidneys. '*' significantly different at p-value < 0.05.

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