From: Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis
VEGF Metric
Effect of a decrease in isoform length
Effect of VEGF cleavage
Level of Soluble VEGF
↑ [21]
↑ [7]
Level of Bound VEGF
↓ [24]
↓ [19] *
Level of Total VEGF
= [7] *
= [7, 19] *
Magnitude of soluble VEGF gradients
↓ [13]
↓ [17]
Spatial Range of soluble VEGF
↑ [12]
↑ [17]