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Table 1 Correlation between protein network structure and miRNA activity

From: Detecting microRNAs of high influence on protein functional interaction networks: a prostate cancer case study

 

Protein connectivity

Clustering coefficient

 

R2 (p-value)

R2 (p-value)

FPI-TargetScan

0.73 (0.004)

-0.77 (0.01)

HPRD-TargetScan

0.85 (0.001)

-0.28 (0.2)

FPI-miRecord

0.80 (0.002)

-0.148(0.8)

HPRD-miRecord

0.64 (0.009)

-0.537(0.02)

Random

-0.26 (0.54)

0.22 (0.5)

  1. Spearman’s rank correlation of protein connectivity and clustering coefficient vs. number of targeting miRNAs, significance of correlation is indicated by p-value in brackets, FDR < 0.005.
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BMC Systems Biology

ISSN: 1752-0509

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