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Table 5 Parameter values adopted in the model

From: Computational modeling of apoptotic signaling pathways induced by cisplatin

Reaction rate constants

k1+

1 μM-1 s-1

  

k20+

1 μM-1 s-1

  

k2+

0.5 μM-1 s-1

  

k21+

1 μM-1 s-1

  

k3+

1 μM-1 s-1

k3-

1 s-1

k22+

1 μM-1 s-1

k22-

1 s-1

k4+

1 s-1

  

k23+

1 s-1

  

k5+

1 μM-1 s-1

k5-

1 s-1

k24+

1 μM-1 s-1

k24-

1 s-1

k6+

1 s-1

  

k25+

1 μM-1 s-1

k25-

1 s-1

k7+

10 μM-1 s-1

k7-

0.5 s-1

k26+†

10 μM-1 s-1

  

k8+

1 s-1

  

k27+

1 μM-1 s-1

k27-

1 s-1

k9+†

10 μM-1 s-1

K9-†

0.5 s-1

k28+

1 s-1

  

k10+†

0.1 s-1

  

k29+

0.5 μM-1 s-1

  

k11+

1 μM-1 s-1

  

k30+

0.5 μM-1 s-1

  

k12+†

5 μM-1 s-1

K12-†

0.0035 s-1

k31+

1 μM-1 s-1

  

k13+†

5 μM-1 s-1

K13-†

0.0035 s-1

k32+

0.5 μM-1 s-1

  

k14+

0.5 μM-1 s-1

  

k33+

1 μM-1 s-1

k33-

1 s-1

k15+

0.5 μM-1 s-1

  

k34+

1 s-1

  

k16+

1 μM-1 s-1

k16-

1 s-1

k35+

1 μM-1 s-1

k35-

1 s-1

k17+

1 s-1

  

k36+

1 s-1

  

k18+

1 μM-1 s-1

k18-

1 s-1

k37+

1 μM-1 s-1

  

k19+

1 s-1

      
  1. †, cited parameters [44]. Unit of reaction rate constant: M–1 s–1 for bimolecular reactions, s–1 for monomolecular reactions [44].
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BMC Systems Biology

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