Process | Rate constant | Value in the model, s-1 | Existing experimental estimates, s-1 | Reference |
---|---|---|---|---|
mRNA synthesis induced by ER2-hormone complexes | k sr | 0.195 | 0.125-0.2 | [74] |
mRNA synthesis induced by ER2-inhibitor complexes | k sr,i | 0.02 | - | Â |
mRNA synthesis induced by ER2-hormone-inhibitor complexes | k sr,hi | 0.05 | - | Â |
mRNA synthesis induced by ER2 | k sr,b | 0.001 | - | Â |
mRNA degradation | k dr * | (0.0025)* | 0.001-0.003 | [74] |
 |  |  | 1.5×10-4-0.005 | [75] |
Protein synthesis | k sp * | (0.001)* | 3×10-4 - 0.03 | [76] |
Protein degradation | k dp * | (2×10-5)* | 1.4×10-5 -3×10-5 | [76] |
Constant ratio | κ | 5×10-5 |  |  |